What is the main ingredient in buprenorphine?

Each sublingual tablet contains 8 mg of buprenorphine (as buprenorphine hydrochloride). Excipients with known effect: Each tablet contains 175.6 mg of lactose monohydrate and 0.76 mg of sunset yellow (E110).

What are the two main ingredients in Suboxone?

Suboxone contains two ingredients: buprenorphine and naloxone.

• Buprenorphine’s role. Buprenorphine has some of the same effects as opioid drugs, but it also blocks other effects of opioids.
• Naloxone’s role. Naloxone is included in Suboxone solely to help prevent abuse of the medication.
• Phases of treatment.

What is buprenorphine powder?

Buprenorphine hydrochloride is a white powder, weakly acidic and with limited solubility in water. Buprenex (buprenorphine) is a clear, sterile, injectable agonist-antagonist analgesic intended for intravenous or intramuscular administration.

Is buprenorphine effective if swallowed?

by Drugs.com While swallowing Subutex (buprenorphine) is unlikely to be harmful, it will reduce how much medicine your body takes in and make the medicine much less effective. Subutex is readily absorbed into your bloodstream through the gastrointestinal and mucosal membranes.

What is the brand name of buprenorphine?

Buprenorphine is intended for the treatment of pain (Buprenex®) and opioid addiction (Suboxone® and Subutex®).

Why is buprenorphine given sublingually?

Buprenorphine oral/sublingual (given under the tongue) is used to treat opioid addiction. Other forms of buprenorphine are used to treat moderate to severe pain. Buprenorphine sublingual is not for use as a pain medication. Buprenorphine sublingual may also be used for purposes not listed in this medication guide.

Why is buprenorphine prescribed?

Buprenorphine and the combination of buprenorphine and naloxone are used to treat opioid dependence (addiction to opioid drugs, including heroin and narcotic painkillers).

What happens when you swallow a sublingual pill?

Swallowing it may cause some of the needed drug to be excreted, and result in a dose too low to be effective. She also advises consumers to keep the candy-tasting medicines out of children’s reach.

What happens if you just swallow Suboxone?

Taken orally, as is the case with Suboxone, the naloxone has no action. If swallowed, the medication does not get absorbed into the blood stream via the stomach or intestines. This is the reason the manufacturers combined naloxone with buprenorphine.

How many mg of buprenorphine is in a sublingual tablet?

Each sublingual tablet contains 8 mg of buprenorphine (as buprenorphine hydrochloride). Excipients with known effect: Each tablet contains 175.6 mg of lactose monohydrate and 0.76 mg of sunset yellow (E110). For the full list of excipients, see section 6.1. 3.

Is it safe to take Buprenorphine under the tongue?

Physicians must warn patients that the sublingual route is the only effective and safe route of administration for this medicinal product (see section 4.4). Buprenorphine sublingual tablets are to be placed under the tongue until dissolved. The tablet should not be swallowed, crushed or chewed.

What happens if you take one dose of buprenorphine?

Even one dose of this medicine (buprenorphine sublingual tablets) may be deadly if it is taken by someone else or by accident, especially in children. If this medicine (buprenorphine sublingual tablets) is taken by someone else or by accident, get medical help right away.

What to do if NNRTIs is added to buprenorphine?

(7) • Antiretrovirals: Patients who are on chronic buprenorphine treatment should have their dose monitored if NNRTIs are added to their treatment regimen. Monitor patients taking buprenorphine and atazanavir with and without ritonavir, and reduce dose of buprenorphine if warranted.