Is octamethylcyclotetrasiloxane safe?

Octamethylcyclotetrasiloxane is classified as toxic for reproduction category 3. The substance is not regulated in an Annex to the Cosmetics Directive nor has it been evaluated by the Scientific Committee on Cosmetology (SCC) /SCCNFP before.

What is octamethylcyclotetrasiloxane used for?

Octamethylcyclotetrasiloxane (D4; CAS No. 556-67-2) is used as a monomer in the manufacture of polymeric materials, which are widely used in various industrial and/or medical applications, such as breast implants.

Is octamethylcyclotetrasiloxane a silicone?

General description. Octamethylcyclotetrasiloxane (D4) is a volatile methylsiloxane (VMS) with a relatively low molecular weight. This silicone fluid has a silicon-oxygen bond in a cyclic arrangement and methyl groups are attached to the silicon atom.

Is octamethylcyclotetrasiloxane volatile?

Octamethylcyclotetrasiloxane (D4) is a volatile cyclic siloxane used primarily as a monomer or intermediate in the production of some silicon-based polymers widely used in industrial and consumer applications and may be present as a residual impurity in a variety of consumer products.

Is octamethylcyclotetrasiloxane soluble in water?

It is a colorless viscous liquid. It is a common cyclomethicone. It is widely used in cosmetics….Octamethylcyclotetrasiloxane.

Names
Melting point	17–18 °C (63–64 °F; 290–291 K)
Boiling point	175–176 °C (347–349 °F; 448–449 K)
Solubility in water	56.2±2.5 ppb (23 °C)
log P	6.98±0.13

How are cyclic silicones prepared?

Silicones are prepared by the hydrolysis of alkyl or aryl substituted silicon halides. Alkyl or aryl substituted silicon halides are prepared by passing gaseous alkyl or aryl halide over an alloy of copper and silicon at 300°C. Cyclic silicones may be obtained by the hydrolysis and subsequent, condensation of R2SiCl2.

What is D4 siloxane?

D4, also known as cyclotetrasiloxane, octamethyl-, is an industrial chemical.

Is Cyclotetrasiloxane good for hair?

Is Cyclotetrasiloxane D4 Safe? Like so many of the chemicals in personal care products, this one has been generally considered safe—particularly in rinse-off products like conditioners.

Is dimethicone bad in moisturizer?

Research shows that the level of dimethicone found in personal care products is safe. It’s also noncomedogenic and won’t clog pores. “From a health perspective, there is no reason to avoid products with dimethicone. They have a nice cosmetic feel and do a good job moisturizing the skin and hair,” Pierre says.

What can octamethylcyclotetrasiloxane be used for?

Octamethylcyclotetrasiloxane (D4) is a volatile methylsiloxane (VMS) with a relatively low molecular weight. This silicone fluid has a silicon-oxygen bond in a cyclic arrangement and methyl groups are attached to the silicon atom. D4 can be used in the manufacture of silicone based polymers for use in medical devices and personal care products.

Where was octamethylcyclotetrasiloxane found in Singapore?

Octamethylcyclotetrasiloxane was found in both the influent and the post-aerated waste water at a sewage treatment facility in Singapore, date not given(1). It has also been detected as a volatile emission from refuse landfills(2).

What happens when you inhale octamethylcyclotetrasiloxane ( D4 )?

Inhalation of octamethylcyclotetrasiloxane (D4) induces CYP2B1/2 protein and causes liver enlargement. We have developed a pharmacodynamic (PD) extension to a physiologically based pharmacokinetic (PBPK) model to characterize these dose-response behaviors.

What is the melting point of D4 cyclotetrasiloxane?

Additional physical and chemical specifications D4 D5 Melting point: 17.5°C – 44.2 °C Boiling point: 175°C 211.0 °C Flash point: / / Vapour pressure: 0.681 torr at 20°C 0.148 torr at 23 °C Density: 0.95 0.96 Viscosity: / 3.87 cst pKa: / / Refractive index: / / Surface tension: / 18.5 dyne/cm at 25 °C D4