What is the function of carbonic anhydrase 2?
What is the function of carbonic anhydrase 2?
CA II is an enzyme of the family of carbonic anhydrases (CAs), which are a group of zinc-containing proteins that catalyze the reversible conversion between carbon dioxide and bicarbonate [305]. In humans, they are involved in gluconeogenesis, lipogenesis, osteoclast differentiation, acid-base balance and VC [306,307].
Which transition metal is found in carbonic anhydrase enzyme?
zinc metalloenzyme
This enzyme, named carbonic anhydrase, was identified as the first zinc metalloenzyme. For both the in vivo function and the use of CA in sensors, the affinity and selectivity of metal ion binding to the active site is key.
What is carbonic anhydrase cofactor?
-Carbonic anhydrase is classified as metalloenzymes due to the presence of metal ion zinc. -The enzyme maintains acid-base balance and helps in the transport of carbon dioxide. -Its cofactor is zinc which helps in various physiological processes of higher vertebrates.
Is zinc a cofactor for carbonic anhydrase?
Carbonic anhydrase is a metalloenzyme that requires Zn as a cofactor and is involved in diverse biological processes including pH regulation, CO2 transfer, ionic exchange, respiration, CO2 photosynthetic fixation, and stomatal closure.
What does the enzyme carbonic anhydrase cause?
Summary: Carbonic anhydrase is an enzyme that balances the pH of the blood and enables the breathing out of carbon dioxide. In red blood cells carbonic anhydrase catalyzes the reaction to convert carbon dioxide into carbonic acid, which further breaks down into bicarbonate ions and protons (H+).
What would happen without carbonic anhydrase?
What would happen if no carbonic anhydrase were present in red blood cells? Without carbonic anhydrase, carbon dioxide would not be hydrolyzed into carbonic acid or bicarbonate. Therefore, very little carbon dioxide (only 15 percent) would be transported in the blood away from the tissues.
Where is carbonic anhydrase synthesized?
Carbonic anhydrase, enzyme found in red blood cells, gastric mucosa, pancreatic cells, and renal tubules that catalyzes the interconversion of carbon dioxide (CO2) and carbonic acid (H2CO3). Carbonic anhydrase plays an important role in respiration by influencing CO2 transport in the blood.
