What is a distant recurrence?

Listen to pronunciation. (DIS-tunt ree-KER-ents) Cancer that has recurred (come back) in another part of the body that is far away from where the original (primary) tumor first formed.

What stage is distant cancer?

Other Ways to Describe Stage

Stage	What it means
Stage I, Stage II, and Stage III	Cancer is present. The higher the number, the larger the cancer tumor and the more it has spread into nearby tissues.
Stage IV	The cancer has spread to distant parts of the body.

What does it mean when cancer is distant?

Refers to cancer that has spread from the original (primary) tumor to distant organs or distant lymph nodes.

What does distant recurrence risk mean?

Distant recurrence (metastasis) occurs when cancer spreads beyond the breast and nearby lymph nodes to other organs such as the bones, liver, lungs or brain. The risk of distant recurrence is the same for people who have lumpectomy plus radiation therapy and those who have mastectomy [154].

Can local recurrence be cured?

In many cases, local and regional recurrences can be cured. Even when a cure isn’t possible, treatment may shrink your cancer to slow the cancer’s growth. This can relieve pain and other symptoms, and it may help you live longer.

Is Local Stage 4 recurrence?

If the cancer is detected in surrounding lymph nodes to the original location, it is a regional recurrence. If the cancer has spread to distant parts of the body, it is called metastatic recurrence. Metastatic cancer is also called stage 4.

Is recurrence of cancer worse?

Cancer recurrence may seem even more unfair then. Worse, it’s often more aggressive in the younger cancer survivor – it may grow and spread faster. This aggressiveness means that it could come back earlier and be harder to treat.

How do you stop HER2 recurrence?

Vaccine Derived from HER2 Protein May Help Prevent Breast Cancer Recurrence. A new breast cancer vaccine that is derived from the HER2 protein may help prevent recurrence in patients with HER2-positive disease and appears safe.

How much does chemo reduce risk of recurrence?

Chemotherapy did appear to have some benefit in women who were age 50 or younger with a recurrence score of 16 to 25. For this age group, there were 2% fewer cases of cancer returning for recurrence scores between 16 to 20, and 7% fewer cases for scores between 21 to 25.

Which is the best definition of distant recurrence?

Distant recurrence: Metastatic disease-breast cancer that has either been biopsy confirmed or clinically diagnosed as recurrent invasive breast cancer. Death attributable to any cause, including breast cancer, non-breast cancer, or unknown cause. Contralateral invasive breast cancer.

What does it mean to have a recurrence of cancer?

Local recurrence means that the cancer is in the same place as the original cancer or very close to it. Regional recurrence means that the tumor has grown into lymph nodes or tissues near the original cancer. Distant recurrence means the cancer has spread to organs or tissues far from the original cancer.

When do distant recurrences of breast cancer occur?

Within each group of women, distant recurrences occurred steadily during the 20 years after diagnosis. Specific 20-year risks of distant recurrence were: As the researchers expected, the annual rates of death from breast cancer were low during the first 5 years after initial diagnosis.

What is the risk of distant recurrence of T1 cancer?

For example, women diagnosed with T1 cancer with zero positive lymph nodes had less than a 1% risk of distant recurrence per year for 5 to 20 years after diagnosis. This works out to be a cumulative risk of distant recurrence of 13% 20 years after diagnosis. Cumulative risk of distant recurrence at 20 years was: