What is Cystosarcoma phyllodes of the breast?

Phyllodes tumor—once more commonly referred to as cystosarcoma phyllodes (from Greek kystis [“sac, bladder”], sarkoma [“fleshy tumor”], and phyllon [“leaf”])—is a rare, predominantly benign tumor that occurs almost exclusively in the female breast.

What causes breast phyllodes tumor?

Experts don’t know what causes phyllodes tumors. Women who have a rare genetic disease called Li-Fraumeni syndrome are more likely to have them. They rarely affect men. Women of any age can get phyllodes tumors, but they’re most common in your 40s.

What does a phyllodes tumor look like on ultrasound?

On ultrasound, an inhomogeneous, solid-appearing mass is the most common manifestation. A solid mass containing single or multiple, round or cleft like cystic spaces and demonstrating posterior acoustic enhancement strongly suggests the diagnosis of phyllodes tumor.

Can fibroadenoma turn into Phyllodes?

The transformation of a benign fibroadenoma into a phyllodes tumor is uncommon and unpredictable. We report the case of a 40-year-old woman with a core biopsy proven fibroadenoma that underwent transformation into a malignant phyllodes tumor after 3 years of size stability.

What does a phyllodes tumor feel like?

The first sign is often a lump under your skin. The lump will feel smooth to the touch. The skin over your breast might also turn red and feel warm. The tumor may grow quickly enough that you can eventually see it under your skin.

Are phyllodes tumors bad?

Phyllodes tumors tend to grow quickly, but they rarely spread outside the breast. Although most phyllodes tumors are benign (not cancerous), some are malignant (cancerous) and some are borderline (in between noncancerous and cancerous).

Are phyllodes tumors movable?

Fibroadenomas grow up to 2-3 cm and then stop growing but phyllodes tumors grow continually and sometimes are to 40 cm big. Both these lesions have two components, epithelial and stromal. Clinically fibroadenomas are well circumscibed, hard, oval, movable lesions.

What is the difference between phyllodes tumor and fibroadenoma?

Do phyllodes tumors need to be removed?

Most phyllodes tumors are benign. They may look very much like common benign breast tumors called fibroadenomas. Often, the pathologist needs to look at the whole tumor under the microscope to make a diagnosis. This is why surgery to remove a phyllodes tumor is recommended, even if it is thought to be benign.

Where does a cystosarcoma phyllodes tumor come from?

Phyllodes tumors (from Greek: phullon leaf), also cystosarcoma phyllodes, cystosarcoma phylloides and phylloides tumor, are typically large, fast-growing masses that form from the periductal stromal cells of the breast. They account for less than 1% of all breast neoplasms.

Is the phyllodes tumor of the breast benign?

[1] [2] Most phyllodes tumors are benign. About 1 in 10 are cancerous. [1] The underlying cause of these tumors in unknown. [3] Surgery is the main treatment. Because the tumors can reoccur if they are not removed with enough surrounding tissue, the tumor and at least 1 cm of tissue should be removed.

What’s the average age of a phyllodes tumor?

Phyllodes tumors account for less than 0.3-1% of all breast neoplasms. It is predominantly a tumor of adult women, with very few examples reported in adolescents. The occurrence is most common between the ages of 40 and 60, before the menopause (peak incidence ~45 years).

What’s the survival rate for phyllode sarcoma?

The SArcoma and PHYllode Restrospective (SAPHYR) Study reported a three year survival rate for benign and borderline phyllodes tumors of 100 percent. Other studies have reported similar findings. [4] Malignant tumors have a higher chance of coming back. If the tumor metasticizes, common locations include the lung, mediastinum, and skeleton. [3]