How do you store anhydrous DMSO?

Published by Charlie Davidson on

How do you store anhydrous DMSO?

Keep container tightly closed in a dry and well-ventilated place. This is to avoid instances of exposure to contaminants and conditions of deterioration. If you can afford, store it under inert gas; DMSO is hygroscopic and therefore will attract air into itself, losing its worth with time.

Is dimethyl sulfoxide anhydrous?

DMSO Anhydrous Grade is Dimethyl Sulfoxide (DMSO) with an extremely low moisture content that is produced under exacting manufacturing conditions to ensure dryness. This product eliminates the need for further solvent purification and processing.

How do you make anhydrous DMSO?

Vacuum Distillation Method. A convenient method of preparing nearly anhydrous DMSO is to add approximately 20% excess DMSO to the reaction vessel and remove the excess and water by slow distillation through a packed column under vacuum.

What is DMSO in cell culture?

DMSO (Dimethyl Sulfoxide) is a polar, aprotic organic solvent that is commonly used as a cryoprotectant because of its membrane penetrating and water displacement properties. It is added to cell culture media to reduce ice formation and thereby prevent cell death during the freezing process.

Why is DMSO toxic?

DMSO can cause contaminants, toxins, and medicines to be absorbed through the skin, which may cause unexpected effects. DMSO is thought to increase the effects of blood thinners, steroids, heart medicines, sedatives, and other drugs. In some cases this could be harmful or dangerous.

Should DMSO be refrigerated?

First you may need to study the stability of your compound in DMSO. If there is no degradation while dissolving DMSO, you can store the solution in a refrigerator. Freezing might cause crystallizing your compound, and hence there could be a concentration gradient between top and bottom of the solution.

What is the purpose of DMSO?

Dimethyl sulfoxide (DMSO) is an organic polar aprotic molecule with an amphipathic nature that is ideal for dissolving poorly soluble polar and non-polar molecules. DMSO is widely used as solvent in toxicology and pharmacology, for cryopreservation of cells, and as penetration enhancer during topological treatments.

Is DMSO hazardous?

Contact with the skin may cause stinging and burning and lead to an odor of garlic on the breath. An excellent solvent that can transport toxic solutes through the skin. High vapor concentrations may cause headache, dizziness, and sedation.

How do you evaporate DMSO?

If you used DMSO as solvent, you can remove most of time by connecting a oil pump to a evaporator and then pump your sample overnight.

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