What is tumoral calcinosis?

Hyperphosphatemic familial tumoral calcinosis (HFTC) is a condition characterized by an increase in the levels of phosphate in the blood (hyperphosphatemia) and abnormal deposits of phosphate and calcium (calcinosis) in the body’s tissues.

How is tumoral calcinosis treated?

Surgical excision of the masses has been the only partially effective treatment. A new therapeutic approach, consisting of a low-calcium and low-phosphorus diet and large oral doses of aluminum hydroxide-containing antacids, resulted in marked clinical and radiographic improvement in a patient with tumoral calcinosis.

How is tumoral calcinosis diagnosed?

Owing to the characteristic soft-tissue calcifications of tumoral calcinosis, CT plays a primary role in diagnosis. In cases of advanced disease, the condition may be identified on radiographs. MRI is often performed after CT to evaluate for spinal cord signal abnormalities and for presurgical planning.

Is tumoral calcinosis painful?

Tumoral calcinosis is a rare familial condition characterized by painless, periarticular masses.

Is calcinosis rare?

This is a rare condition that has many different causes. These range from infection and injury to systemic diseases like kidney failure. Often calcinosis cutis has no symptoms.

Who treats tumoral calcinosis?

A nephrologist, a rheumatologist, and/or a hematologist should be consulted, as indicated by the underlying disease.

Can calcinosis go away?

Often calcinosis cutis has no symptoms. But in some cases, it can be very painful. Treatments are available, including surgery, but the calcium lesions may recur.

How do you get rid of calcinosis cutis?

Treatment / Management

1. Diltiazem. Diltiazem is the most commonly used treatment for calcinosis cutis.
2. Warfarin.
3. Bisphosphonates.
4. Minocycline.
5. Ceftriaxone.
6. Aluminum Hydroxide.
7. Probenecid.
8. Topical Sodium Thiosulfate.

Is metastatic calcification reversible?

It is partially reversible by parathyroidectomy in some patients, in contrast to large vessel calcification.

What do you need to know about tumoral calcinosis?

Tumoral calcinosis is a rare familial condition characterized by painless, periarticular masses. The term should be strictly used to refer to a disease caused by a hereditary metabolic dysfunction of phosphate regulation associated with massive periarticular calcinosis and should not be used to refer to soft-tissue calcification in general.

Is the periarticular calcinosis of the soft tissues rare?

Massive periarticular calcinosis of the soft tissues is a unique but not rare radiographic finding. On the contrary, tumoral calcinosis is a rare familial disease.

Are there any other diseases similar to calcinosis?

There are many conditions with similar appearances, including the calcinosis of chronic renal failure, calcinosis universalis, calcinosis circumscripta, calcific tendonitis, synovial osteochondromatosis, synovial sarcoma, osteosarcoma, myositis ossificans, tophaceous gout, and calcific myonecrosis.

What is the medical term for soft tissue calcification?

The term should be strictly used to refer to a disease caused by a hereditary metabolic dysfunction of phosphate regulation associated with massive periarticular calcinosis and should not be used to refer to soft-tissue calcification in general. The condition predominantly affects young black patients with an equal M:F.