What is extragenic sequence?

We describe a remarkably conserved nucleotide sequence, the many copies of which may occupy up to 1% of the genomes of E. coli and S. This sequence, the REP (repetitive extragenic palindromic) sequence, is about 35 nucleotides long, includes an inverted repeat, and can occur singly or in multiple adjacent copies.

What is repetitive extragenic palindromic?

Repetitive extragenic palindromic sequences (REPs) are a distinct class of abundant repeats important in regulation of certain bacterial functions. REPs are found dispersed throughout the chromosome in many bacterial species, often in high copy number. They represent, for example, up to 1% of E.

What is extragenic DNA?

Extragenic region entry In ExtraTrain “extragenic region” is defined as the DNA space between two genes of a genome. The extragenic region entry displays the sequences of the extragenic region and the proteins codified by the two bordering genes. It facilitates the evaluation of the genetic context.

Why genes and Extragenic DNA is important?

The DNA sequence of a gene can be used to predict the mRNA sequence, and the genetic code can in turn be used to predict the amino acid sequence. Genetics: The study of the patterns of inheritance of specific traits.

What does Extragenic mean?

: not involving or not entering into the composition of the genes mutations due to extragenic causes.

What is a palindrome site?

A palindromic sequence is a sequence made up of nucleic acids within double helix of DNA and/or RNA that is the same when read from 5′ to 3′ on one strand and 5′ to 3′ on the other, complementary, strand. It is also known as a palindrome or an inverted-reverse sequence.

What is the palindromic sequence recognized by EcoRI?

In molecular biology it is used as a restriction enzyme. EcoRI creates 4 nucleotide sticky ends with 5′ end overhangs of AATT. The nucleic acid recognition sequence where the enzyme cuts is G↓AATTC, which has a palindromic, complementary sequence of CTTAA↓G.

What are three functions of DNA?

DNA now has three distinct functions—genetics, immunological, and structural—that are widely disparate and variously dependent on the sugar phosphate backbone and the bases.

What are the functions of DNA between genes?

DNA is the molecule that encodes the genetic instructions enabling a cell to produce the thousands of proteins it typically needs. The linear sequence of the A, T, C, and G bases in what is called coding DNA determines the particular protein that a short segment of DNA, known as a gene, will encode.

How does a suppressor mutation work?

A suppressor mutation is a second mutation that alleviates or reverts the phenotypic effects of an already existing mutation in a process defined synthetic rescue. Genetic suppression therefore restores the phenotype seen prior to the original background mutation.