What can cause Dilantin toxicity?

What can cause Dilantin toxicity?

Phenytoin toxicity can occur from an increase in the daily dose of phenytoin, changes in the formulations or brands as well as changes in the frequency of administration. It can also occur when patients are started on new medications that interact with the metabolism or binding capacity of phenytoin to plasma proteins.

Can you take calcium with phenytoin?

Calcium supplementation may be beneficial for people taking anticonvulsant drugs. However, some studies indicate that antacids containing calcium carbonate may interfere with the absorption of phenytoin and perhaps other anticonvulsants.

Does phenytoin decrease calcium levels?

Phenytoin, also, directly decreases calcium absorption leading to hypocalcaemia. It also causes vitamin K deficiency.

How does Dilantin cause osteoporosis?

Anticonvulsant therapy causes changes in calcium and bone metabolism and may lead to decreased bone mass with the risk of osteoporotic fractures. The two widely used antiepileptic drugs phenytoin and carbamazepine are recognized to have direct effects on bone cells.

Can you take vitamin D with phenytoin?

phenytoin cholecalciferol Using phenytoin together with cholecalciferol may decrease the effects of cholecalciferol. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications.

Can you take calcium with Dilantin?

Interactions between your drugs Using calcium carbonate together with phenytoin may decrease the effects of phenytoin. Separate the times of administration of calcium carbonate and phenytoin by at least two to three hours.

What vitamins should not be taken with Dilantin?

Long term use of phenytoin (Dilantin) can deplete your vitamin D levels leading to the potential for other problems. Vitamin D is one that we store, so you will have a reserve to last you at first.

Is it safe to take vitamin D with phenytoin?