Can Olanzapine cause catatonia?

Can Olanzapine cause catatonia?

We are reporting a unique case of Olanzapine induced TD which presented along with catatonia. Both the disorders showed significant improvement with Clozapine. We recommend use of Clozapine for the management of cases of TD with catatonia.

What receptors does Olanzapine work?

The activity of olanzapine is achieved by the antagonism of multiple neuronal receptors including the dopamine receptor D1, D2, D3 and D4 in the brain, the serotonin receptors 5HT2A, 5HT2C, 5HT3 and 5HT6, the alpha-1 adrenergic receptor, the histamine receptor H1 and multiple muscarinic receptors.

Is Olanzapine safe for child?

Olanzapine has been shown in a study to be better than placebo (an inactive pill that looks like the medication) for treating bipolar disorder and schizophrenia in children and adolescents. Olanzapine is approved for the treatment of these disorders in children and adolescents in the United States.

Which is better haloperidol or Olanzapine?

Results: Olanzapine demonstrated clinical results superior to those of haloperidol on overall improvement according to the BPRS and on every secondary measure, including depression. Olanzapine was also associated with significantly fewer discontinuations of treatment due to lack of drug efficacy or adverse events.

Does olanzapine cause dystonia?

[1] Even low dose of olanzapine can cause dystonic reaction. Dystonia is sustained muscle contractions frequently causing twisting and repetitive movements or abnormal postures.

Can antipsychotics cause catatonia?

Furthermore, administration of antipsychotic medications can cause a catatonic episode. This is known as neuroleptic-induced catatonia and has been reported with both typical and atypical antipsychotics9,10,11,12,13.

Does olanzapine cause brain damage?

Sustained use of the antipsychotic olanzapine in patients with remitted psychotic depression was associated with a thinning of the cortex, when compared with placebo, according to a study published online in JAMA Psychiatry.

When does olanzapine kick in?

How long does it take to start working? It can take four to six weeks for olanzapine to show its full effects, but some studies show a good effect for some people within the first week of taking it. You should stay in touch with your doctor to see how it goes over the first few weeks.