What are caffeic acid derivatives?

Caffeic acid (CA) is a phenolic compound synthesized by all plant species and is present in foods such as coffee, wine, tea, and popular medicines such as propolis. This phenolic acid and its derivatives have antioxidant, anti-inflammatory and anticarcinogenic activity.

What is caffeic acid used for?

Caffeic acid is used in supplements for boosting athletic performance, exercise-related fatigue, weight loss, cancer, HIV/AIDS, herpes, and other conditions.

Is caffeic acid water soluble?

Product Info

Cas No.	331-39-5
Synonym	3,4-Dihydroxycinnamic acid
Melting Point	212-214°C(dec.)
Solubility	Sparingly soluble in hot water, PBS (0.6 mg/mL). Soluble in ethanol (25 mg/mL, warm), DMSO (40 mg/mL), DMF (7 mg/mL), ethyl acetate, chloroform, methanol.
Appearance	Brownish/yellowish crystalline powder

Does coffee have caffeic acid?

Caffeic acid is a chemical found in many plants and foods. Coffee is the primary source of caffeic acid in the human diet. However, it can be found in other food sources such as apples, artichoke, berries, olives, and pears. Wine also contains a significant amount of caffeic acid.

What contains ellagic acid?

Ellagic acid is a naturally occurring substance. The best sources of ellagic acid in the diet are strawberries, raspberries, blackberries, cherries, and walnuts.

Is caffeic acid present in coffee?

Caffeic acid (3,4-dihydroxycinnamic acid) is a well-known phenolic phytochemical present in many foods, including coffee. Recent studies suggested that caffeic acid exerts anticarcinogenic effects, but little is known about the underlying molecular mechanisms and specific target proteins.

Is caffeic acid safe?

Some skin and body care companies add caffeic acid to products because of its antioxidant properties. A handful of manufacturers offer caffeic acid supplements. Most research has found that caffeic acid can slow or reverse inflammation. Research has also found that caffeic acid is safe, even in relatively large doses.

What foods are high in chlorogenic acid?

Chlorogenic acid can be found in foods and herbs such as apples [5,6,7,8,9], artichoke [10], betel [11], burdock [12], carrots [13,14,15], coffee beans [5,7,8,9,11], eggplants [5], eucommia [16], grapes [8], honeysuckle [7], kiwi fruit [9], pears [5], plums [5,6], potatoes [5,7,17,18], tea [8,11], tobacco leaves [5].

How do you dissolve caffeic acid?

Caffeic acid is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide, which should be purged with an inert gas.

Is caffeic acid toxic?

Is caffeic acid carcinogenic?

Caffeic acid is possibly carcinogenic to humans (Group 2B).