What does it mean when your gamma globulin is high?

High levels may indicate infection, inflammatory disease or immune disorders. High globulin levels may also indicate certain types of cancer, such as multiple myeloma, Hodgkin’s disease, or malignant lymphoma.

What does low gamma globulin indicate?

Low levels of gamma globulins suggest the under-production of antibodies as found in certain genetic diseases (bubble boy agammaglobulinemia) and leukemia. Other tests can more accurately identify which fraction or sub-component of gamma globulins may be abnormal (protein immunofixation, free kappa or lambda chains).

What autoimmune disease causes low globulin?

Renal disease, hepatic dysfunction, celiac disease, inflammatory bowel disease (IBD) and acute hemolytic anemia can cause the globulin levels to drop. This is also a sign that proteins taken in by the digestive system are not being broken down or absorbed properly.

Can high globulin be treated?

Since hypergammaglobulinemia is caused by other conditions, there aren’t many direct treatment options available. But you can improve or cure this condition by treating other underlying infections, immune disorders, and diseases. One uncommon treatment for this condition is immunoglobulin replacement therapy.

What are the symptoms of high globulin?

Investigating the cause of a raised globulin level

• Bone pain (myeloma).
• Night sweats (lymphoproliferative disorders).
• Weight loss (cancers).
• Breathlessness, fatigue (anaemia).
• Unexplained bleeding (lymphoproliferative disorders).
• Symptoms of carpal tunnel syndrome (amyloidosis).
• Fever (infections).

Is low gamma globulin bad?

A low ratio can be a sign of autoimmune disorders, poor kidney function, or liver disease. A high ratio may indicate certain types of cancer or genetic conditions. The results of a globulin test are not used alone.

Can low globulin be treated?

A doctor will tailor treatment directly to the cause of the low protein. Treatment can also vary depending on a person’s diet, health status, age, and medical history. A doctor may need to carry out a thorough medical history, physical examination, and diagnostic tests to determine the cause of hypoproteinemia.

Can stress cause high globulin?

After the first exposure to stress a relative alpha1-globulin increase was observed. After 10 stress exposures the hitherto neutral stimulus alone produced a conditioned increase in the alpha1-globulin fraction.