What does widening pulse pressure indicate?

What does widening pulse pressure indicate? A widened (or larger) pulse pressure occurs with several diseases, including aortic regurgitation, aortic sclerosis (both heart valve conditions), severe iron deficiency anemia (reduced blood viscosity), arteriosclerosis (less compliant arteries), and hyperthyroidism (increased systolic pressure). Why is widened pulse pressure bad? Having a wide Read more…

Is tacrine a cholinergic agent?

Is tacrine a cholinergic agent? Tacrine is a centrally acting acetylcholinesterase inhibitor and indirect cholinergic agonist (parasympathomimetic). It was the first centrally acting cholinesterase inhibitor approved for the treatment of Alzheimer’s disease, and was marketed under the trade name Cognex. What class of drug is tacrine? Tacrine is a member Read more…