What causes podocyte injury?

What causes podocyte injury? The major causes (genetic or acquired) of foot processes effacement are impaired formation of the slit diaphragm complex, abnormality of the GBM or adhesion of podocytes to the GBM, abnormalities in the cytoskeleton or associated proteins, and alterations in the apical membrane domain of the podocyte. Read more…

What is the meaning of Totto-chan?

What is the meaning of Totto-chan? Totto-chan, the Little Girl at the Window is an autobiographical memoir written by Japanese television personality and UNICEF Goodwill Ambassador Tetsuko Kuroyanagi. The book was published originally as 窓ぎわのトットちゃん (Madogiwa no Totto-chan) in 1981, and became an “instant bestseller” in Japan. What kind of Read more…