Why is Zosyn and vancomycin given together?

Why is Zosyn and vancomycin given together? -Give piperacillin-tazobactam before Vancomycin, as Zosyn possesses broader coverage and can be given more rapidly than vancomycin. -Concomitant use of Vancomycin and piperacillin-tazobactam may increase the incidence of acute kidney injury. Does combination therapy with vancomycin and piperacillin-tazobactam increase the risk of nephrotoxicity Read more…