What role do MDM2 and MDM4 proteins play in cells?
What role do MDM2 and MDM4 proteins play in cells? For more than 25 years, MDM2 and its homolog MDMX (also known as MDM4) have been shown to exert oncogenic activity. These two proteins are best understood as negative regulators of the p53 tumor suppressor, although they may have additional Read more…