How does PBP2a work?
How does PBP2a work? PBP2a is a unique transpeptidase that is not inhibited well by β-lactam antibiotics. Hence, it is able to continue peptidoglycan crosslinking in the face of the challenge by these antibiotics, when other PBPs with transpeptidase activity are inhibited. Crosslinking of peptidoglycan strands in cell-wall synthesis. Does Read more…