What mimics CIDP?

What mimics CIDP?

Several other conditions have similar symptoms, including:

• Guillain-Barre syndrome.
• Lewis-Sumner syndrome.
• Multifocal motor neuropathy.
• Charcot-Marie-Tooth disease.
• Multiple sclerosis.

Can CIDP be misdiagnosed?

Chronic inflammatory demyelinating polyneuropathy (CIDP) is frequently misdiagnosed. Of the clinical phenotypes, “atypical” CIDP is most vulnerable to misdiagnosis.

What can be mistaken for myasthenia gravis?

Beware: there are other diseases that mimic myasthenia gravis. A number of disorders may mimic MG, including generalized fatigue, amyotrophic lateral sclerosis (ALS), Lambert-Eaton myasthenic syndrome, botulism, penicillamine-induced myasthenia, and congenital myasthenic syndromes.

Is CIDP a form of cancer?

Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune peripheral neuropathy frequently described in association with several types of cancer, especially hematologic malignancies.

Does CIDP worsen?

Key points about CIDP This might get worse over time, or it might come and go. Early treatment is important to limit disease progression. It includes medicines or other treatments to suppress the immune system.

What is the life expectancy of someone with myasthenia gravis?

Myasthenia gravis can range from mild to severe. In some cases, symptoms are so minimal that no treatment is necessary. Even in moderately severe cases, with treatment, most people can continue to work and live independently. Life expectancy is normal except in rare cases.

What do you need to know about CIDP?

The diagnosis or confirmation of CIDP needs to be differential with other factors leading to chronic polyneuropathy, such as metabolism, drug interaction, toxicology, and connective tissue diseases.

What kind of demyelination is involved in CIDP?

The presence of multifocal demyelination is common. The pathogenesis of CIDP involves an inflammatory cell infiltrate, segmental demyelination, especially in the paranodal region, followed by remyelination by Schwann cells. The result of this process is defective nodal segments with sheaths of thinner myelin [ 1 ].

What are the different types of CIDP syndrome?

CIDP can be classified as classical and variant types, the latter of which is rare, including pure motor, pure sensory, distal acquired demyelinating symmetric (DADS) neuropathy, multifocal acquired demyelinating sensory and motor (MADSAM, also known as Lewis-Sumner syndrome) neuropathy, etc. [ 1]

Which is more sensitive to steroid therapy CIDP or madsam?

In contrast, CIDP without IgM monoclonal obulinemia is sensitive to steroid therapy; (4) MADSAM: there is limb asymmetrical sensorimotor peripheral neuropathy, which is clinically similar to multifocal motor neuropathy (MMN), but there is also evidence of sensory damages and no anti-ganglioside GM 1 antibody titer. [ 4]