What does piperidine smell like?

Piperidine is a clear, colorless liquid and has a strong pepper- or amine-like pungent odor (Lewis 1993; Trochimowicz et al. 1994).

Why is piperidine toxic?

* Breathing Piperidine can irritate the nose and throat causing coughing and wheezing. * Exposure to Piperidine can cause nausea, vomiting, salivation and abdominal pain. * Exposure can cause headache, dizziness, muscle weakness, fatigue, depression and irritability. * Piperidine may affect the liver and kidneys.

Is piperidine a drug?

Thioridazine is a piperidine antipsychotic drug that was previously widely used in the treatment of schizophrenia and psychosis. Due to concerns about cardiotoxicity and retinopathy at high doses, this drug is now prescribed less than previously and is mostly used for refractory cases.

What does piperidine mean?

: a toxic liquid heterocyclic base C5H11N that has a peppery ammoniacal odor and is obtained usually by hydrolysis of piperine.

What is piperidine used for?

Piperidine is used as a raw material for pharmaceuticals, agrochemicals, rubber chemicals, surface-active agents and other organic chemicals. A review on catalytic hydrogenation of pyridine was published in Advances in Catalysis.

Does piperidine dissolve in water?

Piperidine appears as a clear colorless liquid with a pepper-like odor. Less dense than water, but miscible in water. Will float on water.

Is piperidine a nucleophilic?

Electron withdrawing groups reduce basicity (and nucleophilicity), such as in morpholine versus piperidine (sigma acceptors) and acetamide (pi acceptor) versus ethylamine.

What are the uses of piperidine?

Piperidine

• Prepn of crystalline derivatives of aromatic nitro compd containing nuclear halogen atoms.
• Solvent and intermediate, curing agent for rubber and epoxy resins, catalyst for condensation reactions, ingredient in oils and fuels, complexing agent.

Is piperidine a base?

Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. It is a metabolite of cadaverine, a polyamine found in the human intestine. It has a role as a reagent, a protic solvent, a base, a catalyst, a plant metabolite, a human metabolite and a non-polar solvent.

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